Healing the Whole Self: Addiction, Mental Health & Recovery with Mark Hrymoc, MD on The Way Out Podcast

Recovery is about more than just stopping substance use — it’s about restoring a person’s mind, body, relationships, and sense of self. In The Way Out Podcast episode “Healing the Whole Self: Addiction, Mental Health & Recovery,” host Jason R. sits down with Mental Health Center co-founder and addiction psychiatrist Mark Hrymoc, MD to explore what true healing really looks like. Addiction and Mental Health Are Deeply Connected As Dr. Hrymoc explains, addiction and mental health disorders rarely exist in isolation. Depression, anxiety, trauma, ADHD — when left untreated, they can fuel substance use. And in turn, addiction often intensifies these same mental health conditions. That’s why treating just one issue isn’t enough. Recovery requires addressing both — together. “Addiction and mental health feed off each other. Recovery means treating the whole person, not just the substance use,” says Dr. Hrymoc. What Real Recovery Means Recovery isn’t simply abstinence. It’s …

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What NRX-100 and NRX-101 Could Mean for Suicide-Focused Depression Carement

Medically Reviewed by Mark Hrymoc, M.D., Chief Medical Officer, double-board certified in General & Addiction Psychiatry Suicidal ideation in major depressive disorder and bipolar depression remains a public health emergency, with U.S. deaths by suicide reaching historically high levels in recent years. Against this backdrop, NRx Pharmaceuticals has advanced two investigational agents that target this gap: NRX-100, a preservative-free intravenous ketamine, and NRX-101, an oral fixed-dose combination of D-cycloserine and lurasidone. Understanding how FDA pathways such as Fast Track and Accelerated Approval work, and where these programs may apply, helps clarify what patients, families, and clinicians might expect as development moves forward. Where NRX-100 and NRX-101 Fit Clinically NRX-100 is being studied for rapid relief of acute suicidal ideation in depression, including bipolar depression. Ketamine’s rapid antidepressant effect is well documented, but its clinical use has been limited by temporary benefit and the need for monitored infusion. A proprietary, preservative-free …

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How to Deal with Negative Self-Talk

Medically Reviewed by Mark Hrymoc, M.D., Chief Medical Officer, double-board certified in General & Addiction Psychiatry Negative self-talk is a common yet harmful internal dialogue that can significantly impact mental health. It involves critical, self-defeating thoughts that erode self-esteem and reinforce anxiety, depression, and self-doubt. These internal messages often become automatic, repeating themselves over time and shaping how we perceive ourselves, our abilities, and our worth. Learning to recognize and reframe negative self-talk is a crucial step in building emotional resilience and supporting overall well-being. What Is Negative Self-Talk? Negative self-talk includes the internal narratives that are overly critical, pessimistic, or self-sabotaging. Examples include thoughts like “I’m not good enough,” “I always mess things up,” or “No one cares what I have to say.” These thoughts are often rooted in cognitive distortions, such as black-and-white thinking, catastrophizing, or personalizing. According to Beck’s cognitive model of depression, these patterns can create …

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Mental Health Care for Caregivers: 5 Supportive Strategies

Medically Reviewed by Mark Hrymoc, M.D., Chief Medical Officer, double-board certified in General & Addiction Psychiatry As the population ages and the need for care for elderly and dependent adults grows, the mental health of their caregivers has become a pressing concern. The responsibilities shouldered by family members and professional caregivers can be overwhelming, significantly impacting their well-being and the quality of care provided. Recent research underscores the necessity of mental health support tailored specifically to caregivers in this demographic. Barriers to Seeking Help Despite the clear need for mental health support, many caregivers face obstacles when trying to access care. Stigma surrounding mental health, the pressures of caregiving, and limited awareness of available resources can discourage caregivers from seeking help. A 2023 study in The Journal of Health and Social Behavior reported that only 25% of caregivers experiencing anxiety or depression pursued professional help, underlining the need for increased …

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5 Tips on Navigating Caregiving

By Ashley Barnes, M.S. Caregivers Rosalind Carter, former First Lady of the United States once said that “there are only four kinds of people in this world: those who have been caregivers, those who are currently caregivers, those who will be caregivers and those who will need caregivers. Caregiving is universal.” A caregiver is a paid or unpaid member of a person’s social network who looks after a sick, elderly, or disabled person. Oftentimes, caregivers are family members. Caregivers assist a person with tasks of daily living such as grocery shopping and cooking, housework, transportation, medical care, bathing, managing personal services (like talking to doctors or paying bills), and much more. Caregiving can be mentally, emotionally, and physically taking for caregivers which can then impact the quality of caregiving. The following are tips on how to better navigate caregiving in a way that is beneficial to both the caregiver and …

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